Forskning

En viktig grundpelare i Stockholm IVFs verksamhet är anknytningen till forskningen. Alla våra läkare och embryologer är antingen disputerade (har erhållit Med Dr examen) inom Reproduktionsmedicin eller bedriver doktorandarbete mot Med Dr examen. Våra medarbetare vid Stockholm IVF producerar enskilt betydligt fler forskningsartiklar än vad övriga 7 privata IVF kliniker i Sverige gör. Detta gör att vi håller oss vid den internationella forskningsfronten inom ett flertal fält. Vi har forsknings samarbete med IVF-enheterna vid internationella ledande kliniker såsom vid Harvard Medical School, Yale University, Cleveland Clinic och Tokyo University.

 

Artiklarna från 2014, 2015 och 2016 anges nedan.

Research articles

 

Live donors of the initial observational study of uterus transplantation-Psychological and medical follow up until 1 year after surgery in the 9 cases.

Hellström M, Bandstein S, Brännström M.

Ann Biomed Eng. 2016 Dec 19. [Epub ahead of print]

PMID: 27995397

 


 

Monitoring of human uterus transplantation with cervical biopsies - a provisional scoring system for rejection.

Mölne J, Broecker V, Ekberg J, Nilsson O, Dahm-Kähler P, Brännström M.

Am J Transplant. 2016 Nov 21. doi: 10.1111/ajt.14135. [Epub ahead of print]

PMID: 27868389

 


 

Molecular characterization of insulin resistance and glycolytic metabolism in the rat uterus.

Zhang Y, Sun X, Sun X, Meng F, Hu M, Li X, Li W, Wu XK, Brännström M, Shao R, Billig H.

Sci Rep. 2016 Jul 27;6:30679. doi: 10.1038/srep30679.

PMID: 27461373

 


 

Uterine transplantation is not a good use of limited resources: AGAINST: It is a highly effective infertility treatment.

Brännström M, Dahm-Kähler P, Diaz-Garcia C.

BJOG. 2016 Aug;123(9):1440. doi: 10.1111/1471-0528.13962. No abstract available.

PMID: 27440590

 


 

One uterus bridging three generations: first live birth after mother-to-daughter uterus transplantation.

Brännström M, Bokström H, Dahm-Kähler P, Diaz-Garcia C, Ekberg J, Enskog A, Hagberg H, Johannesson L, Kvarnström N, Mölne J, Olausson M, Olofsson JI, Rodriguez-Wallberg K.

Fertil Steril. 2016 Aug;106(2):261-6. doi: 10.1016/j.fertnstert.2016.04.001.

PMID: 27125227

 


 

Bioengineered uterine tissue supports pregnancy in a rat model.

Hellström M, Moreno-Moya JM, Bandstein S, Bom E, Akouri RR, Miyazaki K, Maruyama T, Brännström M.

Fertil Steril. 2016 Aug;106(2):487-496.e1. doi: 10.1016/j.fertnstert.2016.03.048.

PMID:27068301

 


 

Human uterus transplantation in focus.

Dahm-Kähler P, Diaz-Garcia C, Brännström M.

Br Med Bull. 2016 Mar;117(1):69-78. doi: 10.1093/bmb/ldw002.

PMID: 26888381

 


 

Attitudes towards new assisted reproductive technologies in Sweden: a survey in women 30-39 years of age.

Wennberg AL, Rodriguez-Wallberg KA, Milsom I, Brännström M.

Acta Obstet Gynecol Scand. 2016 Jan;95(1):38-44. doi: 10.1111/aogs.12781.

PMID: 26399953

 


 

Prostaglandin E2 and vascular endothelial growth factor A mediate angiogenesis of human ovarian follicular endothelial cells.

Trau HA, Brännström M, Curry TE Jr, Duffy DM.

Hum Reprod. 2016 Feb;31(2):436-44. doi: 10.1093/humrep/dev320.

PMID: 26740577

 


 

Chemokine Ligand 20: A Signal for Leukocyte Recruitment During Human Ovulation?

Al-Alem L, Puttabyatappa M, Rosewell K, Brännström M, Akin J, Boldt J, Muse K, Curry TE Jr.

Endocrinology. 2015 Sep;156(9):3358-69. doi: 10.1210/en.2014-1874.

PMID: 26125463

 


 

Livebirth after uterus transplantation - Authors' reply.

Brännström M, Diaz-Garcia C, Johannesson L, Dahm-Kähler P, Bokström H.

Lancet. 2015 Jun 13;385(9985):2352-3. doi: 10.1016/S0140-6736(15)61098-4. No abstract available.

PMID: 26088638

 


 

Psychological aspects in pre-transplantation assessments of patients prior to entering the first uterus transplantation trial.

Järvholm S, Johannesson L, Brännström M.

Acta Obstet Gynecol Scand. 2015 Oct;94(10):1035-8. doi: 10.1111/aogs.12696.

PMID: 26073658

 


 

The Swedish uterus transplantation project: the story behind the Swedish uterus transplantation project.

Brännström M.

Acta Obstet Gynecol Scand. 2015 Jul;94(7):675-9. doi: 10.1111/aogs.12661. No abstract available.

PMID: 25958784

 


 

Obstetric and neonatal outcome of pregnancies fathered by males on immunosuppression after solid organ transplantation.

Morken NH, Diaz-Garcia C, Reisaeter AV, Foss A, Leivestad T, Geiran O, Hervás D, Brännström M.

Am J Transplant. 2015 Jun;15(6):1666-73. doi: 10.1111/ajt.13159.

PMID: 25868657

 


 

Induction of proteinases in the human preovulatory follicle of the menstrual cycle by human chorionic gonadotropin.

Rosewell KL, Al-Alem L, Zakerkish F, McCord L, Akin JW, Chaffin CL, Brännström M, Curry TE Jr.

Fertil Steril. 2015 Mar;103(3):826-33. doi: 10.1016/j.fertnstert.2014.11.017.

PMID: 25516084

 


 

Uterus transplantation trial: 1-year outcome.

Johannesson L, Kvarnström N, Mölne J, Dahm-Kähler P, Enskog A, Diaz-Garcia C, Olausson M, Brännström M.

Fertil Steril. 2015 Jan;103(1):199-204. doi: 10.1016/j.fertnstert.2014.09.024.

PMID: 25439846

 


 

Livebirth after uterus transplantation.

Brännström M, Johannesson L, Bokström H, Kvarnström N, Mölne J, Dahm-Kähler P, Enskog A, Milenkovic M, Ekberg J, Diaz-Garcia C, Gäbel M, Hanafy A, Hagberg H, Olausson M, Nilsson L.

Lancet. 2015 Feb 14;385(9968):607-16. doi: 10.1016/S0140-6736(14)61728-1.

PMID: 25301505

 


 

Uterus transplantation trial: Psychological evaluation of recipients and partners during the post-transplantation year.

Järvholm S, Johannesson L, Clarke A, Brännström M.

Fertil Steril. 2015 Oct;104(4):1010-5. doi: 10.1016/j.fertnstert.2015.06.038.

PMID: 26231464

 


 

Uterus transplantation.

Brännström M.

Curr Opin Organ Transplant. 2015 Dec;20(6):621-8. doi: 10.1097/MOT.0000000000000246. Review.

PMID: 26536423

 


 


Ethics of uterus transplantation with live donors.

Olausson M, Johannesson L, Brattgård D, Diaz-Garcia C, Lundmark C, Groth K, Marcickiewizc J, Enskog A, Akouri R, Tzakis A, Rogiers X, Janson PO, Brännström M.

Fertil Steril. 2014 Jul;102(1):40-3. doi: 10.1016/j.fertnstert.2014.03.048. No abstract available.

PMID: 24784936

 


 

First clinical uterus transplantation trial: a six-month report.

Brännström M, Johannesson L, Dahm-Kähler P, Enskog A, Mölne J, Kvarnström N, Diaz-Garcia C, Hanafy A, Lundmark C, Marcickiewicz J, Gäbel M, Groth K, Akouri R, Eklind S, Holgersson J, Tzakis A, Olausson M.

Fertil Steril. 2014 May;101(5):1228-36. doi: 10.1016/j.fertnstert.2014.02.024.

PMID: 24582522

 


 

Differential expression of inflammation-related genes in the ovarian stroma and granulosa cells of PCOS women.

Schmidt J, Weijdegård B, Mikkelsen AL, Lindenberg S, Nilsson L, Brännström M.

Mol Hum Reprod. 2014 Jan;20(1):49-58. doi: 10.1093/molehr/gat051.

PMID: 23900753

 


 

Ovarian membrane-type matrix metalloproteinases: induction of MMP14 and MMP16 during the periovulatory period in the rat, macaque, and human.

Puttabyatappa M, Jacot TA, Al-Alem LF, Rosewell KL, Duffy DM, Brännström M, Curry TE Jr.

Biol Reprod. 2014 Aug;91(2):34. doi: 10.1095/biolreprod.113.115717.

PMID: 24920038

 


 

Towards the development of a bioengineered uterus: comparison of different protocols for rat uterus decellularization.

Hellström M, El-Akouri RR, Sihlbom C, Olsson BM, Lengqvist J, Bäckdahl H, Johansson BR, Olausson M, Sumitran-Holgersson S, Brännström M.

Acta Biomater. 2014 Dec;10(12):5034-42. doi: 10.1016/j.actbio.2014.08.018.

PMID: 25169258

 


 

Allogeneic uterus transplantation in baboons: surgical technique and challenges to long-term graft survival.

Tryphonopoulos P, Tzakis AG, Tekin A, Johannesson L, Rivas K, Morales PR, Wagner J, Mölne J, Enskog A, Diaz-Garcia C, Dahm-Kähler P, Berho M, Zimberg S, Falcone T, Ruiz P, Olausson M, Brännström M.

Transplantation. 2014 Sep 15;98(5):e51-6. doi: 10.1097/TP.0000000000000322. No abstract available.

PMID: 25171537

 


 

The future of human uterus transplantation.

Johannesson L, Dahm-Kähler P, Eklind S, Brännström M.

Womens Health (Lond). 2014 Jul;10(4):455-67. doi: 10.2217/whe.14.22. Review.

PMID: 25259905

 


 

mTORC1 Signaling in oocytes is dispensable for the survival of primordial follicles and for female fertility.

Gorre N, Adhikari D, Lindkvist R, Brännström M, Liu K, Shen Y.

PLoS One. 2014 Oct 22;9(10):e110491. doi: 10.1371/journal.pone.0110491.

PMID: 25338086

 


 

Somatic cells initiate primordial follicle activation and govern the development of dormant oocytes in mice.

Zhang H, Risal S, Gorre N, Busayavalasa K, Li X, Shen Y, Bosbach B, Brännström M, Liu K.

Curr Biol. 2014 Nov 3;24(21):2501-8. doi: 10.1016/j.cub.2014.09.023.

PMID: 25438940

 


 

Pregnancy after allogeneic uterus transplantation in the rat: perinatal outcome and growth trajectory.

Díaz-García C, Johannesson L, Shao R, Bilig H, Brännström M.

Fertil Steril. 2014 Dec;102(6):1545-52.e1. doi: 10.1016/j.fertnstert.2014.09.010.

PMID: 25439799

 

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